A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 33/16 (2006.01) A61L 29/08 (2006.01) A61L 29/16 (2006.01) C12N 11/02 (2006.01) A61M 25/00 (2006.01) C12N 9/20 (2006.01)
Patent
CA 2163560
An improved indwelling catheter (10) adapted for long-term usage includes a stable enzyme coating (14, 40) to prevent occlusion of the catheter lumen (16). The enzyme coating includes a fibrinolytic and/or lipolytic enzyme incorporated in a catheter coating to resist or control proteolytic degradation, thereby maintaining the enzyme in an active state for dissolving clots and occlusions within the catheter lumen over an extended period of time.
La présente invention concerne une amélioration de sonde (10) à demeure. Celle-ci, adaptée à l'utilisation à long terme, comporte un enrobage enzymatique (14, 40) stable destiné à prévenir l'occlusion de la lumière (16) de la sonde. L'enrobage enzymatique comporte un enzyme fibrinolytique et/ou lipolytique incorporé à l'enrobage de la sonde de façon à résister ou à contrôler la dégradation protéolytique. Ce procédé permet de conserver pendant une longue période l'enzyme à l'état actif nécessaire à la dissolution des caillots et des occlusions se produisant dans la lumière de la sonde.
Gowling Lafleur Henderson Llp
Medtronic Minimed Inc.
LandOfFree
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