Methods for treating emesis and central nervous system...

Details Methods for treating emesis and central nervous system... Methods for treating emesis and central nervous system...

A - Human Necessities

61

K

A61K 31/445 (2006.01) A61K 31/4468 (2006.01) A61K 31/495 (2006.01)

Patent

CA 2245768

Compositions employing and methods utilizing the optically pure (+) isomer of norcisapride are disclosed. This compound has surprisingly been found to be a potent drug for the treatment of disorders of the central nervous system. The compound, (+) norcisapride, has also been found to be a potent antiemetic agent. Finally, the (+) isomer of norcisapride also avoids certain adverse side effects and certain adverse drug interactions.

L'invention concerne des compositions et des procédés dans lesquels on utilise un isomère (+) optiquement pur de norcisapride. On a découvert avec surprise que ce composé, plus précisément le (+) norcisapride, est un médicament puissant pour le traitement de troubles du système nerveux central, et il est un agent antiémétique puissant. Ledit isomère (+) de norcisapride permet de supprimer certains effets secondaires et interactions médicamenteuses indésirables.

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