Processes for the preparation of sulfonylureas

Details Processes for the preparation of sulfonylureas Processes for the preparation of sulfonylureas

C - Chemistry, Metallurgy

07

D

C07D 239/28 (2006.01) C07C 311/54 (2006.01) C07C 333/12 (2006.01) C07C 381/08 (2006.01) C07D 251/12 (2006.01) C07D 295/205 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2064620

HOE 91/F 099 Abstract of the disclosure Processes for the preparation of sulfonylureas The process according to the invention for the prepara- tion of compounds of the formula (I) or salts thereof Image (I) in which X is -O-, -O-NR2- or -SO2-NR2, Y is N or CH, R1 is a (substituted) alkyl, (substituted) alkenyl or (substituted) alkynyl radical, or, in the case where X is O, also (substituted) phenyl and R2 is H, alkyl, alkenyl, alkynyl or cycloalkyl, and R3, R4, R5 and R5 are as defined in formula I as claimed in claim 1, comprises reacting compounds of the formula II Image (II) in which Z is -S- or -NR3- and R7 and R3 are H, alkyl, (substituted) phenyl or (substituted) benzyl or, in the case where Z is NR3, R7 and NR3 are also a 5- to 7-mem- bered heterocycle, with compounds of the formula III: Image (III)

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