Methods for converting a, ab and b blood types to o blood type

Details Methods for converting a, ab and b blood types to o blood type Methods for converting a, ab and b blood types to o blood type

C - Chemistry, Metallurgy

12

N

C12N 15/56 (2006.01) A61K 35/18 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 9/24 (2006.01) C12S 3/22 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2149641

2149641 9411518 PCTABS00032 A process for producing .alpha.-N-acetylgalactosaminidase by expressing a DNA sequence derived from human placenta encoding .alpha.-N-acetylgalactosaminidase in a recombinant host microorganism transformed with an expression vector containing DNA sequence and isolating transformants having .alpha.-N-acetylgalactosaminidase expression. The isolated transformants are then cultured and .alpha.-N-acetylgalactosaminidase is purified from the culture media. The recombinantly produced .alpha.-N-acetylgalactosaminidase is used to convert A, B and AB blood types into O blood type.

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