Hydroxylated pyrimidyl cyclopentanes as akt protein kinase...

C - Chemistry – Metallurgy – 07 – D

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C07D 239/70 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2711699

The present invention provides compounds, including pharmaceutically acceptable salts thereof, comprising the Formula (I): Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases, such as cancer.

La présente invention concerne des composés, y compris leurs sels pharmaceutiquement acceptables, répondant à la formule (I) : Elle concerne également des procédés d'utilisation des composés de cette invention comme inhibiteurs de protéines kinase Akt et pour le traitement de maladies hyperprolifératives, comme le cancer.

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