Synergistic antimicrobial compositions and methods of...

A - Human Necessities – 61 – L

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A61L 29/08 (2006.01) A01N 25/34 (2006.01) A01N 33/08 (2006.01) A01N 63/02 (2006.01) A61K 38/00 (2006.01) A61K 38/40 (2006.01) A61L 27/34 (2006.01) A61P 31/04 (2006.01) C08J 7/04 (2006.01)

Patent

CA 2452032

A synergistic antimicrobial composition for inhibiting biofilm formation includes an iron-sequestering glycoprotein, a cationic polypeptide and a chelating agent, or an iron- sequestering glycoprotein and a chelating agent, or an iron-sequestering glycoprotein and a cationic polypeptide. Additionally, surfactants and quaternary ammonium compounds may also be advantageously combined with iron-sequestering glycoproteins in an antimicrobial composition. Methods of using a synergistic composition for inhibiting medical device biofilm formation are also disclosed.

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