Biomarkers for alzheimer's disease progression

Details Biomarkers for alzheimer's disease progression Biomarkers for alzheimer's disease progression

A - Human Necessities

61

K

A61K 31/27 (2006.01) A61P 25/28 (2006.01) C12Q 1/68 (2006.01) C40B 30/00 (2006.01)

Patent

CA 2661558

This invention relates generally to the analytical testing of tissue samples in vitro, and more particularly to aspects of genetic polymorphisms associated with the conversion from Mile Cognitive Impairment to dementia, e.g., Alzheimer's Disease (AD). The invention provides AD-associated mutations which are useful in the diagnosis, prognosis or therapeutic treatment of dementia, e.g., Alzheimer's Disease.

Cette invention concerne, de manière générale, le test analytique d'échantillons tissulaires in vitro, et plus particulièrement des aspects des polymorphismes génétiques associés à la conversion de la Déficience Cognitive Légère en démence, comme par exemple, la maladie d'Alzheimer (AD). L'invention fournit des mutations associées à la maladie d'Alzheimer qui sont utiles dans le diagnostic, le pronostic ou le traitement thérapeutique de la démence, comme par exemple, la maladie d'Alzheimer.

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