Method of the administration of drugs having binding...

A - Human Necessities – 61 – K

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A61K 45/06 (2006.01) A61K 31/137 (2006.01) A61K 31/192 (2006.01) A61K 47/06 (2006.01) A61K 51/00 (2006.01) A61K 51/04 (2006.01)

Patent

CA 2376159

A method of the administration of drugs with binding affinity for plasma protein and drugs regulating the effective ingredient dose of drugs with binding affinity for plasma protein; and a preparation whereby the effective ingredient dose of drugs with binding affinity for plasma protein is regulated. The above administration method is characterized in that, in the administration of a first drug having binding affinity for plasma protein, a second drug having binding affinity for the same plasma protein is administered simultaneously with the first drug or before or after the administration of the first drug to thereby regulate the binding of the first drug to the plasma protein.

L'invention se rapporte à un procédé d'administration de médicaments dotés d'une affinité de liaison aux protéines plasmatiques, qui permet une régulation de la dose de principe actif administré. L'invention se rapporte à une préparation permettant une régulation de la dose de principe actif contenue dans les médicaments dotés d'une affinité de liaison aux protéines plasmatiques. Le procédé d'administration ci-dessus se caractérise en ce que lors de l'administration d'un premier médicament doté d'une affinité de liaison aux protéines plasmatiques, un second médicament doté d'une affinité de liaison aux protéines plasmatiques est administré simultanément au premier médicament, ou avant ou après l'administration du premier médicament, dans le but de réguler la liaison de ce premier médicament aux protéines plasmatiques.

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