Real time monitoring of small particle dissolution by way of...

G - Physics – 01 – N

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G01N 21/51 (2006.01) G01N 15/02 (2006.01) G01N 15/06 (2006.01) G01N 33/15 (2006.01) G01N 13/00 (2006.01)

Patent

CA 2494516

A method for determining the percent of a solid material dissolved into a liquid medium is disclosed. The method comprises the steps of combining the solid material and the liquid medium; determining the initial solid concentration (i); determining the dynamic solid concentration (d) using a light scattering technique; and calculating the percent dissolved material according to the formula: [(i - d)/i] x 100 . Methods for determining dissolution rate and particle size using turbidity measurements are also disclosed.

L'invention concerne une méthode servant à déterminer le pourcentage de matériau solide dissout dans un milieu liquide. Cette méthode consiste à combiner le matériau solide et le milieu liquide, à déterminer la concentration solide initiale (i), à déterminer la concentration solide dynamique (d) au moyen d'une technique de diffusion lumineuse et à calculer le pourcentage de matériau dissout en fonction de la formule : [(I-d)/I]x100. Elle concerne également des méthodes servant à déterminer la vitesse de dissolution et la dimension des particules au moyen de mesures de turbidité.

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