C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/14 (2006.01) A61K 31/551 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01) C07D 413/04 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2703904
The present invention is directed to diazepan compounds which are antagonists of orexin receptors, and which are useful in the treatment of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which orexin receptors are involved.
La présente invention porte sur des composés de type diazépan qui sont des antagonistes des récepteurs de l'orexine, et qui sont utiles dans le traitement de troubles et de maladies neurologiques et psychiatriques mettant en jeu les récepteurs de l'orexine. L'invention porte également sur des compositions pharmaceutiques comprenant ces composés et sur l'utilisation de ces composés et de ces compositions dans le traitement de maladies mettant en jeu les récepteurs de l'orexine.
Bergman Jeffrey M.
Coleman Paul J.
Cox Christopher D.
Roecker Anthony J.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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