A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2210193
This invention relates to treatment of traveller's diarrhea, including diarrhea caused by enterotoxigenic E. coli (ETEC), using oligosaccharide compositions which bind E. coli heat-labile toxin (LT) and/or one or more serotypes of enterotoxigenic E. coli organisms. More specifically, the invention concerns neutralization and removal of LT associated with traveller's diarrhea. This invention also relates to prevention of ETEC from colonizing the intestinal tract and inducing disease.
La présente invention concerne le traitement de la diarrhée des voyageurs, dont la diarrhée causée par E. coli entérotoxinogène (ECET), à l'aide de compositions oligosaccharidiques qui fixent la toxine thermolabile (TL) d'E. coli et/ou un sérotype ou plus d'E. coli entérotoxinogène. Plus spécifiquement, l'invention concerne la neutralisation et l'élimination de la TL liée à la diarrhée des voyageurs. L'invention concerne également la prévention de la colonisation des voies intestinales par ECET, l'empêchant ainsi de provoquer la maladie.
Armstrong Glen
Heerze Louis D.
Synsorb Biotech Inc.
Torys Llp
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