C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 1/107 (2006.01) A61K 39/00 (2006.01) A61K 47/48 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2162157
Provided by this invention are essentially homogeneous, defined compositions of matter and hetero-polyoximes of defined structure comprising a baseplate structure having a plurality of oxime bonds, wherein each oxime bond links a specifically active molecule to the baseplate. Also provided are novel baseplates having a plurality of oxime forming complementary reactive groups and novel specifically reactive molecules having an oxime forming complementary reactive group. Also provided by this invention are methods of preparing these novel compositions of matter by chemoselectively ligating via oxime bond formation a complementary orthogonal reactive group on the baseplate to a complementary reactive orthogonal group on a specifically active molecule. Methods of using these defined compositions of matter as well as pharmaceutical compositions comprising these defined compositions of matter and methods of their use are also provided by this invention.
Offord Robin E.
Rose Keith
Offord Robin E.
Robic
Rose Keith
LandOfFree
Polyoxime compounds and their preparation does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Polyoxime compounds and their preparation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polyoxime compounds and their preparation will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2076833