Tsg101-gag interaction and use thereof

Details Tsg101-gag interaction and use thereof Tsg101-gag interaction and use thereof

C - Chemistry, Metallurgy

12

N

C12N 15/49 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 31/18 (2006.01) C07K 14/15 (2006.01) C07K 14/155 (2006.01) C07K 14/16 (2006.01) C07K 14/47 (2006.01) C07K 14/82 (2006.01) C12N 1/19 (2006.01) C12N 15/10 (2006.01) C12N 15/12 (2006.01) C12N 15/48 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G06F 17/50 (2006.01)

Patent

CA 2441071

Isolated protein complexes are provided comprising Tsg101 and HIV GAG or GAGp6. The protein complexes are useful in screening assays for selecting compounds effective in modulating the Tsg101-HIV GAG or GAGp6 interaction within the protein complexes.

L'invention concerne des complexes protéiques isolés comportant Tsg101 et HIV GAG ou HIV GAGp6. Ces complexes protéiques sont utiles dans le cadre de tests de criblage destinés à sélectionner des composés efficaces pour moduler l'interaction Tsg101-HIV GAG ou Tsg101- HIV GAGp6 se produisant dans les complexes protéiques.

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