Thiophene-2-carboxamide derivatives as modulators of ccr9...

C - Chemistry – Metallurgy – 07 – D

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C07D 333/38 (2006.01) A61K 31/425 (2006.01) A61K 31/5377 (2006.01) A61P 29/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2701768

Provided are compounds of Formula (I) or of Formula (II) that are modulators of CCR9 receptor activity, compositions containing the compounds and methods of use of the compounds and compositions. In certain embodiments, provided are methods for treating or amelioratin diseases associated with modulation of CCR9 receptor activity.

La présente invention concerne des composés qui sont des modulateurs de l'activité du récepteur CCR9, des compositions contenant les composés et des procédés d'utilisation des composés et compositions. Dans certains modes de réalisation, l'invention concerne des procédés permettant de traiter ou d'améliorer des maladies associées à la modulation de l'activité du récepteur CCR9.

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