Alkaline phosphatase enzymes having improved specific...

Details Alkaline phosphatase enzymes having improved specific... Alkaline phosphatase enzymes having improved specific...

C - Chemistry, Metallurgy

12

N

C12N 15/55 (2006.01) C12N 9/16 (2006.01) C12Q 1/44 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2138382

The present invention involves the construction of several mutations in the Escherichia coli alkaline phosphatase gene that result in the production of an enzyme having an improved specific activity. The resultant mutant enzymes have up to 1.5- to 36-fold higher specific activity, while retaining a temperature stability that is significantly higher than that of mammalian alkaline phosphatase enzymes. The utility of mutant E. coli alkaline phosphatase as an enzyme label in binding assays is also demonstrated.

Affiliated with

Also associated with

Rating

Alkaline phosphatase enzymes having improved specific... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Alkaline phosphatase enzymes having improved specific..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Alkaline phosphatase enzymes having improved specific... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2077300