Real time method of detecting acute inflammatory conditions

G - Physics – 01 – N

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G01N 33/53 (2006.01) G01N 33/564 (2006.01) G01N 33/566 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2561684

This invention relates to the diagnosis and/or monitoring of patients with inflammatory diseases or conditions, including systemic lupus erythematosus, particularly for activity. This disclosure presents the surprising discovery that levels of complement pathway components on reticulocytes can be used to diagnose, monitor, or predict the occurrence of acute episodes of chronic inflammatory disease or conditions.

Cette invention se réfère au diagnostique et/ou au monitorage de patients souffrant de maladies ou de symptômes inflammatoires, comprenant lupus érythémateux disséminé, en particulier pour le diagnostique du stade aigu de la maladie, y compris des procédés et des kits pour la mise en AEuvre de cette activité. Cette divulgation présente la découverte surprenante que des niveaux de composants de voie complémentaire sur des réticulocytes peuvent être utilisés pour diagnostiquer, monitorer ou prévoir la survenance d'épisodes aigus de maladies ou affections inflammatoire chroniques.

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