New bradykinin b1-antagonists

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 239/28 (2006.01) A61K 31/505 (2006.01) A61P 25/04 (2006.01) A61P 29/00 (2006.01) C07C 237/24 (2006.01) C07C 255/19 (2006.01) C07C 317/44 (2006.01) C07D 209/42 (2006.01) C07D 213/82 (2006.01) C07D 233/90 (2006.01) C07D 237/24 (2006.01) C07D 263/34 (2006.01) C07D 277/56 (2006.01) C07D 307/68 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2697946

The invention relates to compounds of general formula (I), in which n, R1, R2, R3, R4, R5, R6, R7 and R8 are defined as cited in the description, to the enantiomers, diastereomers, mixtures and salts of said compounds, in particular to the physiologically compatible salts thereof with organic or inorganic acids or bases that have valuable properties, to the production thereof, to medicaments containing the pharmacologically active compounds, to their production and their use.

La présente invention concerne des composés de formule générale (I) dans laquelle n, R1, R2, R3, R4, R5, R6, R7 et R8 sont définis tel que mentionné dans la description, leurs énantiomères, leurs diastéréomères, leurs mélanges et leurs sels, en particulier leurs sels physiologiquement tolérés avec des acides ou bases organiques ou minéraux/minérales, qui ont des propriétés intéressantes, leur préparation, des produits pharmaceutiques contenant les composés pharmacologiquement actifs, leur préparation et leur utilisation.

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