Immunogenic cd91 ligand-antigenic molecule complexes and...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 19/00 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2515122

The present invention relates to complexes and fusion proteins comprising a CD91 ligand and an antigenic molecule, for use in the treatment or prevention of a disease. The invention specifically provides complexes comprising a CD91 ligand noncovalently bound to, or alternatively crosslinked to, an antigenic molecule. The invention also specifically provides fusion proteins comprising a CD91 ligand fused via a peptide bond to an antigenic molecule.

L'invention concerne des complexes et des protéines de fusion comprenant un ligand CD91 et une molécule antigène utilisés pour traiter ou prévenir une maladie. De manière plus spécifique, l'invention concerne des complexes comprenant un ligand CD91 lié de manière non covalente à une molécule antigène, ou alternativement réticulé avec celle-ci. L'invention concerne également des protéines de fusion comprenant un ligand CD91 fusionné via une liaison peptidique à une molécule antigène.

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