Oxazole compounds, their production and use

C - Chemistry – Metallurgy – 07 – D

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C07D 263/30 (2006.01) A61K 31/42 (2006.01) C07D 263/32 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2035431

ABSTRACT OF THE DISCLOSURE An oxazole compound having the formula (I): Image (I) in which A is a group of the formula -CH2OR2 (wherein R2 is a hydrogen atom, an optionally substituted hydrocarbon residue, an optionally substituted heterocyclic group or an acyl group) or an aldehyde group, B is an optionally substituted phenyl group, R1 is a hydrogen atom or an optionally substituted alkyl group, and n is an integer of 0 to 6, provided that when n is 2, R1 is an optionally substituted alkyl group, or its salt, which is useful as a therapeutic agent for metabolic bone diseases including osteoporosis.

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