C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 235/30 (2006.01) C07D 235/32 (2006.01) C07D 277/82 (2006.01) C07D 401/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2620857
The invention concerns novel products of formula (I), wherein: A represents NH or S; R1, R2 and R3 represent H, NH2, Hal or Alk, one at least of R1, R2 and R3 being other than hydrogen; R represents in particular: cycloalkyl, alkyl, alkoxy or NR4R5, R4 representing H or Alk and R5 representing cycloalkyl or alkyl optionally substituted by hydroxyl, alkoxy, heteroaryl, heterocycloalkyl, NR6R7, phenyl, phenyl-NR6R7 and CONR6R7, R6 and R7 representing H or Alk or phenyl and R6 and R7 may form together with H a cyclic radical; R4 and R5 may also form together with N a cyclic radical; all the above heterocycloalkyl, heteroaryl and phenyl radicals being optionally substituted, said products being in all the isomeric forms and their salts, as medicines in particular as Met inhibitors.
L'invention concerne les nouveaux produits de formule (I) à titre de médicaments notamment comme inhibiteurs de protéins Limases telles que Met.
Clerc Francois
Nemecek Conception
Aventis Pharma S.a.
Robic
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