Assessment of human papilloma virus-related disease

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/70 (2006.01) C07K 14/025 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2313483

This invention provides novel methods for assessing HPV infection. Gene expression levels are used to the progression of HPV infection from benign to malignant growth by determining the ratio between mRNA levels of E6 and/or E7 and E2 and/or L1. Also provided are kits for carrying out the methods of this invention.

L'invention concerne de nouveaux procédés d'évaluation des infections au virus du papillome humain (VPH). On utilise les niveaux d'expression génique pour évaluer la progression de l'infection à VPH de son stade de développement bénin à son stade malin. L'invention concerne également des kits permettant de mettre en oeuvre les procédés de l'invention.

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