C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 16/42 (2006.01) C12N 15/62 (2006.01)
Patent
CA 2389956
The present invention relates to polynucleotide and polypeptide molecules for zfsta4, a novel member of the follistatin family. The polypeptides, and polynucleotides encoding them are useful for binding to members of the TGF- .beta. family and mediating central nervous system, reproductive, hematopoietic and bone-related activities. The present invention also includes antibodies to the zfsta4 polypeptides.
L'invention concerne des molécules polynucléotidiques et polypeptidiques pour zfsta4, un nouveau membre des la famille follistatine. Ces polypeptides, ainsi que les polynucléotides qui les codent, sont utiles pour fixer les membres des la famille TGF-.beta. et pour assurer une médiation des activités du système nerveux central, de la reproduction, de l'hématopoïèse et des activités associées aux os. L'invention concerne également des anticorps dirigés contre les polypeptides zfsta4.
Conklin Darrell C.
Sheppard Paul O.
Conklin Darrell C.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Sheppard Paul O.
Zymogenetics Inc.
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