Antibacterial wound dressing

A - Human Necessities – 61 – L

Patent

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Details

A61L 15/28 (2006.01) A61L 15/46 (2006.01)

Patent

CA 2458708

An antibacterial wound dressing is based on or derived from gel-forming fibres such as carboxymethyl cellulose or alginate fibres having silver ions linked thereto at some but not all of the exchangeable sites such that the distribution of silver ions over the exchangeable sites is substantially uniform. The silvered fibres for the wound dressing can be prepared by contacting an assembly of precursor gel-forming fibres having exchangeable sites under conditions which do not cause irreversible gelling of the fibres with an amount of a solution containing silver ions so as to link silver ions at some but not all of the exchangeable sites, the whole of the assembly of precursor gel-forming fibres being contacted essentially simultaneously with the entire solution containing silver ions.

L'invention concerne un pansement antibactérien comportant ou fabriqué à partir de fibres gélifiantes telles que la carboxyméthylcellulose ou des fibres d'alginate auxquelles sont liés des ions argent, à certains sites d'échange seulement, de sorte que la distribution d'ions argent sur ces sites est sensiblement uniforme. Les fibres argentées du pansement peuvent être préparées par la mise en contact, dans des conditions n'entraînant pas de gélification irréversible des fibres, d'un ensemble de fibres gélifiantes précurseurs présentant des sites d'échange avec une quantité de solution renfermant des ions argent, de manière à ne lier les ions argent qu'à certains sites d'échange ; l'ensemble complet des fibres gélifiantes précurseurs est mis en contact de manière essentiellement simultanée avec toute la solution renfermant des ions argent.

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