Prevention and/or treatment of allergic conditions

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/335 (2006.01) A61K 31/135 (2006.01) A61K 35/06 (2006.01) A61K 38/55 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2313653

The present invention relates to the use of an inhibitor of cysteine proteinase activity in conjunction with an inhibitor of any serine proteinase activity other than trypsin for the manufacture of a medicament for the prevention or treatment of a condition in which an allergen traverses an epithelial barrier such as asthma. Also included in the invention are formulations and kits containing serine and cysteine proteinase inhibitors and their use in the prevention or treatment of conditions in which an allergen traverses an epithelial barrier.

L'invention concerne l'utilisation d'un inhibiteur de l'activité de cystéine protéinase associé à un inhibiteur de toute activité de sérine protéinase autre que trypsine afin de préparer un médicament servant à prévenir ou à traiter un état dans lequel un allergène traverse une barrière épithéliale, tel que l'asthme. Elle concerne également des formulations et des trousses contenant des inhibiteurs de sérine et de cystéine protéinase, ainsi que leur mise en application prophylactique ou thérapeutique dans des états dans lesquels un allergène traverse une barrière épithéliale.

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