Method for the preparation of citalopram

Details Method for the preparation of citalopram Method for the preparation of citalopram

C - Chemistry, Metallurgy

07

D

C07D 307/87 (2006.01) A61K 31/34 (2006.01) A61K 31/343 (2006.01) A61P 25/24 (2006.01) B01J 31/24 (2006.01) B01J 23/755 (2006.01)

Patent

CA 2290125

Method for the preparation of citalopram comprising reaction of a compound of Formula IV Image wherein R is Cl or Br with a cyanide source in the presence of a nickel catalyst and isolation of the corresponding 5-cyano compound, i.e. citalopram.

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