Plasma protein matrices and methods for their preparation

A - Human Necessities – 61 – L

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Details

A61L 27/40 (2006.01) C12N 5/071 (2010.01) A61L 27/14 (2006.01) A61L 27/22 (2006.01) A61L 27/26 (2006.01) A61L 27/38 (2006.01) A61L 27/54 (2006.01) A61L 27/56 (2006.01) A61L 27/58 (2006.01) C12N 5/00 (2006.01) A61K 35/12 (2006.01)

Patent

CA 2454341

A freeze dried biocompatible matrix comprising plasma proteins, useful as implants for tissue engineering as well as in biotechnology, and methods of producing said matrix are provided. Mechanical and physical parameters can be controlled by use of auxiliary components or additives which may be removed after the matrix is formed in order to improve the biological properties of the matrix. The matrices according to the present invention may be used clinically, per se or as a cell-bearing implant.

Matrice biocompatible lyophilisée comprenant des protéines de plasma utiles en tant qu'implants à des fins d'ingénierie de tissus ainsi qu'en biotechnologie, et procédés pour produire cette matrice polymère. On peut réguler les paramètres mécaniques et physiques en utilisant des composants ou additifs auxiliaires qui peuvent être évacués une fois que la matrice est formée, et ce pour améliorer les propriétés biologiques de la matrice. Les matrices de l'invention peuvent s'utiliser en clinique, directement ou comme implant portant des cellules.

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