A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/55 (2006.01) A61K 31/16 (2006.01) A61K 31/19 (2006.01) A61K 38/04 (2006.01)
Patent
CA 2071972
A pharmaceutical composition for treating or preventing retroviral diseases containing a thiol-protease inhibitor as an active principle. Thiol-protease inhibitors are known products such as cystatines and the derivatives thereof, antipaine [(S)-1-carboxy-2-phenyletyl]-carbamoyl-Arg-Val-Arg-al, E-64 (L-trans-epoxysuccinyl-leucylamide-(4-guanidino)-butane, N-[N-(L-3-transcarboxyirane-2-carbonyl)-L-leucyl]-agmatine, leupeptin, iodoacetic acid/iodoacetamide or N-Cbz-Phe-Ala-diazomethane.
2071972 9108769 PCTABS00105 L'invention se rapporte à une composition pharmaceutique pour le traitement ou la prévention des maladies à rétrovirus comprenant, à titre de principe actif, un inhibiteur de thiol-protéases. Les inhibiteurs de thiol-protéases sont des produits connus; par exemple les cystatines et leurs dérivés, l'antipaïne [(S)-1-carboxy-2-phenylethyl]-carbamoyl-Arg-Val-Arg-al, E-64 (L-trans-epoxysuccinyl-leucylamide-(4-guanidino)-butane, N-[N-(L-3-transcarboxyirane-2-carbonyl)-L-leucyl]-agmatine, la leupeptine, l'acide iodoacétique/iodoacétamide ou le N-Cbz-Phe-Ala-diazométhane.
Guy Bruno
Lecocq Jean-Pierre
Swabey Ogilvy Renault
Transgene S.a.
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