Dried biologically or therapeutically active preparations

Details Dried biologically or therapeutically active preparations Dried biologically or therapeutically active preparations

A - Human Necessities

61

K

A61K 47/18 (2006.01) A61K 9/19 (2006.01) A61K 38/37 (2006.01) A61K 47/26 (2006.01) A61L 2/04 (2006.01)

Patent

CA 2301514

A dried, heat-treated product comprises (i) a heat labile, biologically or therapeutically active protein or peptide preparation and (ii) a stabilising effective amount of a composition comprising sucrose, trehalose and at least one amino acid. The protein or peptide preparation may be, for example, a Factor VIII concentrate or a von Willebrand Factor concentrate.

Produit déshydraté traité thermiquement, qui comprend (i) une préparation de protéines ou de peptides thermolabile, possédant une activité biologique ou thérapeutique, et (ii) une quantité efficace d'une composition stabilisante, comprenant du saccharose, du tréhalose et au moins un acide aminé. La préparation de protéines ou de peptides peut être, par exemple, un concentré de facteur VIII ou un concentré du facteur de von Willebrand.

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