Isolated nucleic acid molecules which encode tage molecules,...

Details Isolated nucleic acid molecules which encode tage molecules,... Isolated nucleic acid molecules which encode tage molecules,...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07H 21/04 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C12N 5/06 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12N 15/85 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2319312

A new family of tumor rejection antigen precursors, and the nucleic acid molecules which code for them, are disclosed. These tumor rejection antigen precursors are referred to as TAGE tumor rejection antigen precursors, and the nucleic acid molecules which code for them are referred to as TAGE coding molecules. Various diagnostic and therapeutic uses of the coding sequences and the tumor rejection antigens, and their precursor molecules are described.

L'invention concerne une nouvelle famille de précurseurs d'antigènes provoquant le rejet de tumeurs et les molécules d'acide nucléique les codant. Ces précurseurs sont appelés précurseurs d'antigènes de rejet de tumeurs TAGE et les molécules d'acide nucléique les codant sont appelées molécules TAGE codantes. Font aussi l'objet de cette invention différentes applications diagnostiques et thérapeutiques des séquences de codage et des antigènes de rejet des tumeurs ainsi que leurs molécules précurseurs.

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