A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/18 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 11/00 (2006.01)
Patent
CA 2661446
The present invention relates generally to a method for treating or preventing or otherwise ameliorating the effects of pulmonary diseases characterized by or associated with infiltration of neutrophils and complications arising therefrom. The present invention further provides agents and pharmaceutical compositions comprising agents which inhibit the activity of G-CSF or its receptor, interfere with G-CSF signaling and/or which down- regulate expression of G-CSF or its receptor.
La présente invention se rapporte en général à une méthode pour traiter ou prévenir, ou sinon améliorer les effets de maladies pulmonaires caractérisés par ou associés à une infiltration de neutrophiles et les complications qui en découlent. La présente invention concerne en outre des agents et des compositions pharmaceutiques qui comprennent des agents qui inhibent l'activité du G-CSF ou de son récepteur, perturbent la signalisation du G-CSF et/ou qui régulent à la baisse l'expression du G-CSF ou de son récepteur.
Crump David Eric
Nash Andrew Donald
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Csl Limited
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