C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/47 (2006.01) A61K 31/505 (2006.01) A61K 31/513 (2006.01) A61K 31/52 (2006.01) C07D 239/48 (2006.01) C07D 473/00 (2006.01) C07D 473/16 (2006.01) C07D 473/18 (2006.01)
Patent
CA 2198739
A method of inhibiting replication of mycoplasmal and Gram-positive bacteria is described. Useful new compounds for in vivo and in vitro inhibition and therapy for infections utilizing HPUra-like compounds are also provided. These include a number of novel 3-substituted uracil and isocytosine compounds, and 10-substituted guanine and adenine compounds.
Procédé permettant d'inhiber la réplication de mycoplasmes et de bactéries Gram positif. On décrit également de nouveaux composés utiles pour l'inhibition in vivo et in vitro et la thérapie des infections, utilisant des composés similaires à HPUra. Ces composés comprennent un certain nombre de composés nouveaux d'uracile substitué en position 3 et d'isocytosine, ainsi que des composés d'adénine et guanine à substitution en position 10.
Brown Neal C.
Wright George
Smart & Biggar
University Of Massachusetts Medical Center
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