Compositions comprising an hiv protease inhibitor such as vx...

Details Compositions comprising an hiv protease inhibitor such as vx... Compositions comprising an hiv protease inhibitor such as vx...

A - Human Necessities

61

K

A61K 31/635 (2006.01) A23L 1/217 (2006.01) A61K 9/48 (2006.01) A61K 31/355 (2006.01) A61P 31/18 (2006.01)

Patent

CA 2249336

Pharmaceutical formulations containing HIV protease inhibitors, specifically including 3S-[3R*(1R*,2S*)]-[3-[[(4- aminophenyl)sulphonyl](2-methylpropyl)-amino]-2-hydroxy-1- phenylmethyl)propyl]carbamic acid, tetrahydro-3-furanyl ester (alternatively known as VX 478 or 141W94), and a tocopherol, and their use in medical therapy are described.

L'invention porte sur des préparations pharmaceutiques contenant des inhibiteurs de la protéase du VIH comportant en particulier un tétrahydro-3-furanyl ester de l'acide 3S-[3R*(1R*,2S*)]-[3-[[(4-aminophényl)sulphonyl](2-méthylpropyl)-amino]-2-hydroxy-1-phénylméthyl)propyl] carbamique (également dénommé VX 478 ou 141W94) ainsi qu'un tocophérol, et sur leur emploi à des fins thérapeutiques.

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