Compositions and method for the treatment of disease

A - Human Necessities – 61 – K

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167/144, 167/148

A61K 31/375 (2006.01) A61K 9/00 (2006.01) A61K 31/07 (2006.01) A61K 31/19 (2006.01) A61K 31/355 (2006.01) A61K 45/08 (2006.01)

Patent

CA 2008739

Synergistic compositions comprising an antioxidant and an arylpropionic, non-steroidal anti-inflammatory drug used to treat certain diseases are disclosed. The compositions inhibit production of arachidonic acid cascade end-products which have been implicated as causes of tissue-destruction in periodontal disease. The compositions are administered in combination with a Carrier, which may be a mucosal-tenacious polymer selected from the groups of semi-solid pastes, gels, ointments, liquids or films.

Compositions synergiques contenant un antioxydant et un anti-inflammatoire non stéroïdien arylpropionique utilisées pour traiter certaines maladies. Ces compositions inhibent la production de produits résultant de la cascade de l'acide arachidonique dont on a déterminé qu'ils provoquaient destruction tissulaire dans les maladies parodontales. Elles sont administrées conjointement à un porteur, qui peut être un polymère tenace dans les muqueuses choisi dans les groupes des pâtes semi-solides, gels, onguents, liquides ou pellicules.

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