Use of lxr agonists for the treatment of osteoarthritis

Details Use of lxr agonists for the treatment of osteoarthritis Use of lxr agonists for the treatment of osteoarthritis

A - Human Necessities

61

K

A61K 31/00 (2006.01) A61K 31/18 (2006.01) A61K 31/195 (2006.01) A61K 31/404 (2006.01) A61K 31/42 (2006.01) A61K 31/513 (2006.01) A61K 31/575 (2006.01) A61K 31/58 (2006.01) G01N 33/68 (2006.01) G01N 33/74 (2006.01) G01N 33/92 (2006.01)

Patent

CA 2662965

Disclosed herein is the use of LXR agonists for preventing and treating osteoarthritis as well as methods of detecting an osteoarthritic phenotype in a subject and methods of identifying an LXR ligand capable of reducing an osteoarthritic effect in cartilage.

L'invention concerne des méthodes de prévention et de traitement de l'ostéoarthrite grâce à l'utilisation d'agonistes LXR.

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