Stable amorphous calcium carbonate comprising phosphorylated...

A - Human Necessities – 61 – K

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A61K 33/10 (2006.01) C07K 14/435 (2006.01)

Patent

CA 2703111

Provided are compositions containing amorphous calcium carbonate (ACC), and at least one phosphorylated amino acid or phosphorylated peptide which stabilizes the amorphous form of said calcium carbonate. Particularly, the peptide can be selected from crustacean proteins, also provided by the invention, namely GAP65, GAP22, GAP21, and GAP12. The compositions are useful in pharmaceutical and nutraceutical formulations.

L'invention porte sur des compositions qui contiennent du carbonate de calcium amorphe et au moins un acide aminé phosphorylé ou peptide phosphorylé qui stabilise la forme amorphe dudit carbonate de calcium. En particulier, le peptide peut être choisi parmi des protéines de crustacés, qui sont également décrites dans l'invention, à savoir GAP65, GAP22, GAP21, et GAP12. les compositions de l'invention sont utilisées dans des formulations pharmaceutiques et nutraceutiques.

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