C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 19/19 (2006.01) A01N 43/04 (2006.01) A61K 31/7076 (2006.01) C07H 19/16 (2006.01) C07H 19/167 (2006.01)
Patent
CA 2627319
The present invention relates to Purine Derivatives; compositions comprising an effective amount of a Purine Derivative; and methods for reducing an animal's core body temperature, protecting an animal's heart against myocardial damage during cardioplegia; or for treating or preventing a cardiovascular disease, a neurological disorder, an ophthalmic condition, an ischemic condition, a reperfusion injury, obesity, a wasting disease, or diabetes, comprising administering an effective amount of a Purine Derivative to an animal in need thereof.
La présente invention concerne des dérivés de purine; des compositions comportant une quantité efficace d'un dérivé de purine; et des procédés pour la réduction de la température corporelle interne d'un animal, protégeant le coeur d'un animal contre un endommagement du myocarde lors d'une cardioplégie; ou pour le traitement et la prévention d'une maladie cardio-vasculaire, d'un trouble neurologique, d'une condition ophtalmologique, d'une condition ischémique, d'une lésion consécutive à la perfusion, de l'obésité, d'une maladie cachectisante, ou du diabète, comprenant l'administration d'une quantité efficace d'un dérivé de purine à un animal qui en a besoin.
Jagtap Prakash
Salzman Andrew L.
Inotek Pharmaceuticals Corporation
Smart & Biggar
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