Use of mcrp to slow cell growth and to promote maturation of...

Details Use of mcrp to slow cell growth and to promote maturation of... Use of mcrp to slow cell growth and to promote maturation of...

A - Human Necessities

61

K

A61K 38/16 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01) C12N 5/16 (2006.01) C12N 5/22 (2006.01) C12P 21/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2341323

The invention provides a method of slowing cell growth and promoting the maturation of cells other than cancer cells and megakaryocyte progenitor cells. The method comprises contacting the cells with a modified C-reactive protein (mCRP) or a mutant-mCRP. The method may be performed in vitro or in vivo.

L'invention concerne un procédé pour ralentir la croissance cellulaire et favoriser la maturation des cellules autres que celles cancéreuses ou souches de mégacaryocytes. Le procédé consiste à mettre les cellules en contact avec une protéine modifiée C-réactive (mCRP) ou avec un mutant-mCRP. Le procédé peut être réalisé in vivo ou in vitro.

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