Monoclonal antibodies against hev orf-2 and methods for...

Details Monoclonal antibodies against hev orf-2 and methods for... Monoclonal antibodies against hev orf-2 and methods for...

C - Chemistry, Metallurgy

12

N

C12N 5/18 (2006.01) C07K 16/10 (2006.01) G01N 33/576 (2006.01)

Patent

CA 2179609

Monoclonal antibodies are described which specifically bind to Hepatitis E Virus (HEV), and more particularly to HEV orf-2 antigen. Also provided are hybridoma cell lines which secrete these monoclonal antibodies, methods for using these monoclonal antibodies, and assay kits which contain these monoclonal antibodies.

L'invention se rapporte à des anticorps monoclonaux qui se lient spécifiquement au virus de l'hépatite E (HEV), et plus particulièrement à l'antigène du deuxième cadre de lecture ouvert (orf-2) de l'HEV. L'invention porte également sur des lignées cellulaires d'hybridomes qui sécrètent ces anticorps monoclonaux, des procédés d'utilisation de ces derniers, ainsi que des kits de dosage les contenant.

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