C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/09 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) C07K 14/47 (2006.01) C07K 14/82 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01) C12N 5/06 (2006.01)
Patent
CA 2276459
The present invention relates to a novel method for testing the developmental status in pancreatic cells of a mammal. The present invention further relates to applications in the medical field that directly arise from the method of the invention. Additionally, the present invention relates to transgenic mammals comprising at least one inactivated Pax4 allele and optionally at least one inactivated Pax6 allele.
La présente invention concerne un nouveau procédé pour tester l'état de développement des cellules pancréatiques chez le mammifère. Le procédé selon l'invention a aussi pour objet des applications directes dans le domaine médical. En outre, l'invention traite de mammifères transgéniques comprenant au moins un allèle Pax4 inactivé et éventuellement au moins un allèle Pax6 inactivé.
Gruss Peter
Sosa-Pineda Beatriz
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.v.
Mbm Intellectual Property Law Llp
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