C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/10 (2006.01) A01K 67/027 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61P 25/28 (2006.01) C12N 15/09 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) C07K 14/57 (2006.01) C07K 16/24 (2006.01) C12N 9/12 (2006.01) C12N 15/23 (2006.01) C12N 15/54 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2612374
This invention is in the field of neurology. Specifically, the invention relates to the discovery and characterization of molecular components that play a role in neuronal demyelination or remyelination. In addition, the invention relates to the generation of an animal model that exhibits hypomyelination. The compositions and methods embodied in the present invention are particularly useful for drug screening and/or treatment of demyelination disorders.
L'invention concerne le champ de la neurologie. Plus spécifiquement, l'invention concerne la découverte et la caractérisation de composants moléculaires qui jouent un rôle dans la démyélinisation ou la remyélinisation neuronales. En outre l'invention concerne la production d'un animal modèle qui présente une hypomyélinisation. Les compositions et procédés de cette invention sont particulièrement utiles pour le criblage de médicaments et/ou le traitement de troubles de démyélinisation.
Lin Wensheng
Popko Brian
Borden Ladner Gervais Llp
University Of Chicago
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