Combinatorial therapies for the treatment of neoplasias...

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/08 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2557504

The present invention relates to pharmaceutical compositions for treating neoplasias in an animal or human comprised of a carrier and therapeutically effective amounts of at least one chemotherapeutic agent along with the biotherapeutic endogenous pentapeptide Met-enkephalin, referred to as opioid growth factor. Also provided are methods of treating neoplasias in an animal or human in need of such treatment, comprising the administration to the animal or human therapeutically effective amounts of a pharmaceutical composition comprised of a carrier and therapeutically effective amounts of at least one neoplasia-treating agent, such as a chemotherapeutic agent or radiation, along with opioid growth factor.

L'invention concerne des compositions pharmaceutiques qui permettent de traiter les néoplasies chez un animal ou un être humain. Ces compositions pharmaceutiques comprennent un excipient et des quantités efficaces sur le plan thérapeutique d'au moins un agent chimiothérapeutique conjointement avec le pentapeptide endogène biothérapeutique Met-enképhaline, appelé facteur de croissance opioïde. L'invention concerne également des méthodes qui permettent de traiter les néoplasies chez un animal ou un être humain nécessitant un tel traitement, ces méthodes consistant à administrer audit animal ou être humain des quantités efficaces sur le plan thérapeutique d'une composition pharmaceutique comprenant un excipient et des quantités efficaces sur le plan thérapeutique d'au moins un agent, tel qu'un agent ou un rayonnement chimiothérapeutique conjointement avec le facteur de croissance opioïde.

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