Melatonin in combination with analgesics

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/40 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2255838

The present invention is a method and composition for potentiating bio- affecting properties of an analgesic agent by administering to mammals (1) at least one analgesic agent and (2) melatonin, wherein said analgesic agent is selected from the group consisting of aspirin, indomethacin, salicylate, dexamethasone, paracetamol, benzydamine hydrochloride, acetaminophen, dipyrone, lapidin, santonin, ibuprofen, indomethacin, oxicam, etodolac, buprenorphine, diclofenac, fentanyl, morphine, nalbuphine, pethidine, and dingetegna.

L'invention concerne un procédé et une composition servant à potentialiser les propriétés à effets biologiques d'un agent analgésique en administrant à des mammifères (1) au moins un agent analgésique et (2) mélatonine. Ledit agent analgésique est sélectionné dans le groupe constitué par aspirine, indométhacine, salicylate, dexaméthasone, paracétamol, hydrochlorure de benzydamine, acétaminophène, dipyrone, lapidine, santonine, ibuprofène, indométhacine, oxicam, étodolac, buprénorphine, diclofénac, fentanyl, morphine, nalbuphine, péthidine et dingetegna.

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