Salts and bases of the 17-(cyclopropylmethyl)-4,5...

Details Salts and bases of the 17-(cyclopropylmethyl)-4,5... Salts and bases of the 17-(cyclopropylmethyl)-4,5...

A - Human Necessities

61

K

A61K 31/485 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2379524

Methods whereby a kappa-preferring opioid blocking agent is used for optimizing dopamine homeostasis during administration of opioid analgesics and for preventing mortal respiratory depression due to drug overdose.

La présente invention concerne des procédés dans lesquels on utilise un agent bloquant opioïde à préférence kappa pour optimiser l'homéostase de la dopamine pendant l'administration d'analgésiques opioïdes et pour prévenir la dépression respiratoire mortelle due à une surdose du médicament.

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