Echinocandin binding domain of 1,3-.beta.-glucan synthase

Details Echinocandin binding domain of 1,3-.beta.-glucan synthase Echinocandin binding domain of 1,3-.beta.-glucan synthase

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) C12N 9/10 (2006.01) C12Q 1/48 (2006.01)

Patent

CA 2255140

The invention relates to a substantially purified ECB binding domain of 1,3-.beta.-glucan synthase, comprising an at least 46 amino acid peptide fragment or fusion protein of glucan synthase that binds echinocanding, useful in a method for identifying new antifungal compounds. Also disclosed are nucleic acid molecules that encode said peptide.

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