Drosophila g protein coupled receptors, nucleic acids, and...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 31/713 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 15/63 (2006.01) C12N 15/86 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2388599

The present invention provides a Drosophila melanogaster GPCR (DmGPCR) polypeptides and polynucleotides which identify and encode such a DmGPCR. In addition, the invention provides expression vectors, host cells and methods for its production. The invention also provides methods for the identification of homologs in other animals, and of DmGPCR agonists/antagonists, useful for the treatment of diseases in animals and for the control of insects that are injurious of harmful to plants or animals.

L'invention concerne des polypeptides de Drosophila melanogaster GPCR (DmGPCR) et des polynucléotides identifiant et codant DmGPCR. Elle concerne, de plus, des vecteurs d'expression, des cellules hôtes et des procédés de préparation. Elle concerne également des procédés servant à identifier des homologues chez d'autres animaux, ainsi que des agonistes/antagonistes de DmGPCR, utiles pour traiter des maladies chez les animaux et pour lutter contre des insectes nocifs pour les plantes ou les animaux.

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