Pharmaceutical compositions

A - Human Necessities – 61 – K

Patent

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A61K 9/10 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2531065

A pharmaceutical composition in the form of a chewable tablet for the suppression of gastric reflux comprising an alginic acid or salt thereof, a water-soluble carbonate radical precursor, a calcium salt, a first bulk sweetener, and a binding agent. The calcium salt and either or both of the bulk sweetener and the binding agent may be blended via any of wet granulation, spray drying, or compression processes prior to admixture with the alginic acid and the carbonate radical precursor.

La présente invention concerne une composition pharmaceutique en dragée de chewing-gum comprenant un acide alginique ou l'un de ses sels, un précurseur hydrosoluble de radical carbonate, un sel de calcul, un premier édulcorant en vrac, et un liant. Le sel de calcium et l'un au moins de l'édulcorant en vrac et du liant peuvent être mélangés par granulation humide, séchage par atomisation ou compression préalablement au mélange à l'acide alginique et au précurseur de radical carbonate.

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