Methods and kits for diagnosis of cancer and prediction of...

A - Human Necessities – 61 – K

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A61K 51/10 (2006.01) A61P 35/00 (2006.01) G01N 33/60 (2006.01)

Patent

CA 2752510

A method for identifying a patient for cancer therapy can include administering a diagnostic dose of a detectably labeled first binding agent to a patient, the detectably labeled binding agent being capable of binding a molecular target. The method also includes selecting a patient for administration of a therapeutic dose of a second binding agent capable of binding a cellular target, wherein the selected patient exhibits a positive reading for the detectably labeled first binding agent. Furthermore, the method can include administering a therapeutic dose of the second binding agent to the patient.

L'invention porte sur un procédé d'identification d'un patient pour une thérapie anti-cancer, qui peut comprendre l'administration à un patient d'une dose diagnostique d'un premier agent de liaison marqué de façon détectable, l'agent de liaison marqué de façon détectable étant capable de se lier à une cible moléculaire. Le procédé comprend également la sélection d'un patient pour l'administration d'une dose thérapeutique d'un second agent de liaison capable de se lier à une cible cellulaire, le patient sélectionné présentant une lecture positive pour le premier agent de liaison marqué de façon détectable. De plus, le procédé peut comprendre l'administration d'une dose thérapeutique du second agent de liaison au patient.

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