Cyclic peptides as potent and selective melanocortin-4...

Details Cyclic peptides as potent and selective melanocortin-4... Cyclic peptides as potent and selective melanocortin-4...

C - Chemistry, Metallurgy

07

K

C07K 7/50 (2006.01) C07K 7/56 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2453027

Cyclic peptides of formula I are potent and selective agonists of melanocortin- 4 receptors, and as such are useful research tool for the determination of the physiological roles of the MC-4 receptor, as well as for the diagnoses, treatment or prevention of disorders or diseases mediated through the MC-4 receptor.

L'invention concerne des peptides cycliques de formule I qui sont des agonistes puissants et sélectifs de récepteurs de mélanocortine-4, et qui, en tant que tels, constituent des outils de recherche utiles pour la détermination des rôles physiologiques du récepteur de MC-4, ainsi que pour les diagnostics, le traitement ou la prévention de troubles ou de maladies dont la médiation est effectuée par le récepteur de MC-4.

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