Glycopeptide antibiotic derivatives

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 7/56 (2006.01) A61K 38/12 (2006.01) A61K 38/14 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2546910

The present invention is directed to glycopeptide antibiotic derivative compounds. These derivative compounds possess antibacterial activity against a wide variety of bacteria, including antimicrobial activity against vancomycin-resistant isolates. The present invention also relates to making and using these glycopeptide antibiotic derivative compounds for the treatment of bacterial infections.

La présente invention concerne des dérivés antibiotiques de glycopeptides. Ces dérivés possèdent une activité antibactérienne contre diverses bactéries, notamment une activité antimicrobienne contre les isolats résistants à la vancomycine. Elle concerne également la fabrication et l'utilisation de ces dérivés antibiotiques de glycopeptides pour le traitement des infections bactériennes.

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