Propanol derivatives

Details Propanol derivatives Propanol derivatives

C - Chemistry, Metallurgy

07

C

260/602

C07C 47/575 (2006.01) A01N 33/10 (2006.01) C07C 215/56 (2006.01)

Patent

CA 1041546

ABSTRACT OF THE DISCLOSURE The invention relates to novel propanol derivatives of the formula: Image (I) wherein R1 represents a hydrogen or halogen atom, a hydroxy or trifluoro- methyl group or an alkyl or alkoxy group with I to 4 carbon atoms; and R2 represents a hydrogen atom, an alkyl group with 1 to 4 carbon atoms or a benzyl group or a pharmaceutically acceptable acid addition salt thereof, and to processes for their preparation. The novel compounds possess sympathicomimetic properties and are potentially useful as cardiac and circulation agents. In particular the novel compounds possess a blood pressure increasing activity. The novel compounds, may, moreover serve as intermediates in the preparation of other physiologically active compounds. Processes for the production of the novel compounds are described and examples of certain of the novel compounds are given. Pharmaceutical compositions containing the novel compounds are described and exemplified.

211135

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